High-throughput sequence-based epigenomic analysis of Alu repeats in human cerebellum

DNA methylation, the only known covalent modification of mammalian DNA, occurs primarily in CpG dinucleotides. 51% of CpGs in the human genome reside within repeats, and 25% within Alu elements. Despite that, no method has been reported for large-scale ascertainment of CpG methylation in repeats. He...

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Detalhes bibliográficos
Main Authors: Xie, Hehuang, Wang, Min, Bonaldo, Maria de F., Smith, Christina, Rajaram, Veena, Goldman, Stewart, Tomita, Tadanori, Soares, Marcelo B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715246/
https://ncbi.nlm.nih.gov/pubmed/19458156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp393
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