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CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA
CUGBP2 (ETR-3/NAPOR/BRUNOL3) promotes inclusion of cardiac troponin T (cTNT) exon 5 via binding between positions 21 and 74 of the downstream intron. The molecular mechanism by which CUGBP2 activates cTNT exon 5 inclusion is unknown. Our results suggest that CUGBP2 promotes exon inclusion by a novel...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715230/ https://ncbi.nlm.nih.gov/pubmed/19443441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp346 |
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