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A Condensation-Ordering Mechanism in Nanoparticle-Catalyzed Peptide Aggregation

Nanoparticles introduced in living cells are capable of strongly promoting the aggregation of peptides and proteins. We use here molecular dynamics simulations to characterise in detail the process by which nanoparticle surfaces catalyse the self-assembly of peptides into fibrillar structures. The s...

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Detalhes bibliográficos
Main Authors: Auer, Stefan, Trovato, Antonio, Vendruscolo, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715216/
https://ncbi.nlm.nih.gov/pubmed/19680431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000458
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