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Zinc transporter Znt5/Slc30a5 is required for the mast cell–mediated delayed-type allergic reaction but not the immediate-type reaction

Zinc (Zn) is an essential nutrient and its deficiency causes immunodeficiency. However, it remains unknown how Zn homeostasis is regulated in mast cells and if Zn transporters are involved in allergic reactions. We show that Znt5/Slc30a5 is required for contact hypersensitivity and mast cell–mediate...

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Detalhes bibliográficos
Main Authors: Nishida, Keigo, Hasegawa, Aiko, Nakae, Susumu, Oboki, Keisuke, Saito, Hirohisa, Yamasaki, Satoru, Hirano, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715059/
https://ncbi.nlm.nih.gov/pubmed/19451265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082533
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