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Tracking the culprit: HIV-1 evolution and immune selection revealed by single-genome amplification

Early control of HIV-1 infection is determined by a balance between the host immune response and the ability of the virus to escape this response. Studies using single-genome amplification now reveal new details about the kinetics and specificity of the CD8(+) T cell response and the evolution of th...

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Autors principals: Brumme, Zabrina L., Walker, Bruce D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715053/
https://ncbi.nlm.nih.gov/pubmed/19487418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091094
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