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Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum

Threats of bioterrorism have renewed efforts to better understand poxvirus pathogenesis and to develop a safer vaccine against smallpox. Individuals with atopic dermatitis are excluded from smallpox vaccination because of their propensity to develop eczema vaccinatum, a disseminated vaccinia virus (...

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Bibliografische gegevens
Hoofdauteurs: Kawakami, Yuko, Tomimori, Yoshiaki, Yumoto, Kenji, Hasegawa, Shunji, Ando, Tomoaki, Tagaya, Yutaka, Crotty, Shane, Kawakami, Toshiaki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715052/
https://ncbi.nlm.nih.gov/pubmed/19468065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082835
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