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Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production
Heme oxygenase–1 (HO-1) is a key cytoprotective, antioxidant, and antiinflammatory molecule. The pathophysiological functions of HO-1 have been associated with its enzymatic activities in heme catabolism. We have examined the immune functions of HO-1 by its conditional ablation in myeloid cells (HO-...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715044/ https://ncbi.nlm.nih.gov/pubmed/19398754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081582 |
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