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IL-4–producing CD4(+) T cells in reactive lymph nodes during helminth infection are T follicular helper cells

Interleukin (IL)-4 is the quintessential T helper type 2 (Th2) cytokine produced by CD4(+) T cells in response to helminth infection. IL-4 not only promotes the differentiation of Th2 cells but is also critical for immunoglobulin (Ig) G1 and IgE isotype-switched antibody responses. Despite the IL-4–...

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Detalhes bibliográficos
Main Authors: King, Irah L., Mohrs, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715031/
https://ncbi.nlm.nih.gov/pubmed/19380638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090313
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