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Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γ

Chlamydiae are obligate intracellular pathogens that are sensitive to pro-inflammatory cytokine interferon-γ. IFN-γ-inducible murine p47 GTPases have been demonstrated to function in resistance to chlamydia infection in vivo and in vitro. Because the human genome does not encode IFN-γ-inducible homo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tietzel, Illya, El-Haibi, Christelle, Carabeo, Rey A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714978/
https://ncbi.nlm.nih.gov/pubmed/19652711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006499
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