High efficiency of HIV-1 genomic RNA packaging and heterozygote formation revealed by single virion analysis

A long-standing question in retrovirus biology is how RNA genomes are distributed among virions. In the studies presented in this report, we addressed this issue by directly examining HIV-1 RNAs in virions using a modified HIV-1 genome that contained recognition sites for BglG, an antitermination pr...

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Main Authors: Chen, Jianbo, Nikolaitchik, Olga, Singh, Jatinder, Wright, Andrew, Bencsics, Craig E., Coffin, John M., Ni, Na, Lockett, Stephen, Pathak, Vinay K., Hu, Wei-Shau
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714765/
https://ncbi.nlm.nih.gov/pubmed/19628694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906822106
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