Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates

Inevitably, viruses depend on host factors for their multiplication. Here, we show that hepatitis C virus (HCV) RNA translation and replication depends on Rck/p54, LSm1, and PatL1, which regulate the fate of cellular mRNAs from translation to degradation in the 5′-3′-deadenylation-dependent mRNA dec...

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Detalhes bibliográficos
Main Authors: Scheller, Nicoletta, Mina, Leonardo Bruno, Galão, Rui Pedro, Chari, Ashwin, Giménez-Barcons, Mireia, Noueiry, Amine, Fischer, Utz, Meyerhans, Andreas, Díez, Juana
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714764/
https://ncbi.nlm.nih.gov/pubmed/19628699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906413106
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