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TNF-α-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells

BACKGROUND: Phosphatidylcholine (PC) is a major lipid of the gastrointestinal mucus layer. We recently showed that mucus from patients suffering from ulcerative colitis has low levels of PC. Clinical studies reveal that the therapeutic addition of PC to the colonic mucus using slow release preparati...

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Detalhes bibliográficos
Main Authors: Treede, Irina, Braun, Annika, Jeliaskova, Petia, Giese, Thomas, Füllekrug, Joachim, Griffiths, Gareth, Stremmel, Wolfgang, Ehehalt, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714528/
https://ncbi.nlm.nih.gov/pubmed/19594939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-9-53
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