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Pigment Epithelium-derived Factor (PEDF) mitigates inflammation and oxidative stress in retinal pericytes exposed to oxidized-LDL

Oxidized and/or glycated LDL may mediate capillary injury in diabetic retinopathy. The mechanisms may involve pro-inflammatory and pro-oxidant effects on retinal capillary pericytes. In this study, these effects, and the protective effects of pigment epithelium-derived factor (PEDF), were defined in...

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Autors principals: Zhang, Sarah X., Wang, Joshua J., Dashti, Azar, Wilson, Kenneth, Zou, Ming-hui, Szweda, Luke, Ma, Jian-xing, Lyons, Timothy J.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714421/
https://ncbi.nlm.nih.gov/pubmed/18586837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-08-0011
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