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Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity

BACKGROUND: Transmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative diseases caused by novel infectious agents referred to as prions. Prions appear to be composed primarily, if not exclusively, of a misfolded isoform of the cellular prion protein. TSE infectivity is r...

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Autori principali: Johnson, Christopher J, Gilbert, PUPA, McKenzie, Debbie, Pedersen, Joel A, Aiken, Judd M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714315/
https://ncbi.nlm.nih.gov/pubmed/19580672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-121
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