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Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage

INTRODUCTION: Disorders that affect glucose metabolism, namely diabetes mellitus (DM), may favor the development and/or progression of osteoarthritis (OA). Thus far, little is known regarding the ability of chondrocytes to adjust to variations in the extracellular glucose concentration, resulting fr...

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Detalhes bibliográficos
Main Authors: Rosa, Susana C, Gonçalves, Juliana, Judas, Fernando, Mobasheri, Ali, Lopes, Celeste, Mendes, Alexandrina F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714130/
https://ncbi.nlm.nih.gov/pubmed/19490621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2713
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