Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis

INTRODUCTION: Anti-TNF therapies have revolutionized the treatment of rheumatoid arthritis (RA), a common systemic autoimmune disease involving destruction of the synovial joints. However, in the practice of rheumatology approximately one-third of patients demonstrate no clinical improvement in resp...

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Main Authors: Hueber, Wolfgang, Tomooka, Beren H, Batliwalla, Franak, Li, Wentian, Monach, Paul A, Tibshirani, Robert J, Van Vollenhoven, Ronald F, Lampa, Jon, Saito, Kazuyoshi, Tanaka, Yoshiya, Genovese, Mark C, Klareskog, Lars, Gregersen, Peter K, Robinson, William H
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714123/
https://ncbi.nlm.nih.gov/pubmed/19460157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2706
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