Large Scale Synthesis of a Persistent Trityl Radical for Use in Biomedical EPR Applications and Imaging

Tetrathiatriarylmethyl radicals are ideal spin probes for biological electron paramagnetic resonance (EPR) spectroscopy and imaging. The wide application of trityl radicals as biosensors of oxygen or other biological radicals was hampered by the lack of affordable large-scale syntheses. We report th...

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Main Authors: Dhimitruka, Ilirian, Velayutham, Murugesan, Bobko, Andrey A., Khramtsov, Valery V., Villamena, Frederick A., Hadad, Christopher M., Zweier, Jay L.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714045/
https://ncbi.nlm.nih.gov/pubmed/17964156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.10.030
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