Regulation of epithelial sodium channels by cGMP/PKGII

Airway and alveolar fluid clearance is mainly governed by vectorial salt movement via apically located rate-limiting Na(+) channels (ENaC) and basolateral Na(+)/K(+)-ATPases. ENaC is regulated by a spectrum of protein kinases, i.e. protein kinase A (PKA), C (PKC), and G (PKG). However, the molecular...

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Autores principales: Nie, Hong-Guang, Chen, Lan, Han, Dong-Yun, Li, Jun, Song, Wei-Feng, Wei, Shi-Peng, Fang, Xiao-Hui, Gu, Xiu, Matalon, Sadis, Ji, Hong-Long
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2009
Materias:
Respiratory
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714029/
https://ncbi.nlm.nih.gov/pubmed/19359370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.170324
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