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Structural Analysis of a β-Helical Protein Motif Stabilized by Targeted Replacements with Conformationally Constrained Amino Acids

Here we study conformational stabilization induced in a β-helical nanostructure by position-specific mutations. The nanostructure is constructed through the self-assembly of the β-helical building block excised from E. coli galactoside acetyltransferase (PDB code 1krr, chain A; residues 131-165). Th...

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Detalhes bibliográficos
Main Authors: Ballano, Gema, Zanuy, David, Jiménez, Ana I., Cativiela, Carlos, Nussinov, Ruth, Alemán, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713822/
https://ncbi.nlm.nih.gov/pubmed/18811190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp8032116
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