Contribution of BRCA1 germ-line mutations to breast cancer in Greece: a hospital-based study of 987 unselected breast cancer cases

BACKGROUND: In most Western populations, 5–10% of all breast cancer cases can be attributed to major genetic factors such as predisposing mutations in BRCA1 and BRCA2, with early-onset cases generally considered as an indicator of genetic susceptibility. Specific BRCA1 and BRCA2 mutations or differe...

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Главные авторы: Armaou, S, Pertesi, M, Fostira, F, Thodi, G, Athanasopoulos, P S, Kamakari, S, Athanasiou, A, Gogas, H, Yannoukakos, D, Fountzilas, G, Konstantopoulou, I
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2009
Предметы:
Clinical Study
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713692/
https://ncbi.nlm.nih.gov/pubmed/19491894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605115
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