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Development, Characterization, and Immunotherapeutic Use of Peptide Mimics of the Thomsen-Friedenreich Carbohydrate Antigen

The tumor-associated carbohydrate Thomsen-Friedenreich antigen (TF-Ag; Galβ1-3GalNAcα-O-Ser/Thr) is overexpressed on the cell surface of several types of tumor cells, contributing to cancer cell adhesion and metastasis to sites containing TF-Ag-binding lectins. A highly specific immunoglobulin G(3)...

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Detalhes bibliográficos
Main Authors: Heimburg-Molinaro, Jamie, Almogren, Adel, Morey, Susan, Glinskii, Olga V, Roy, Rene, Wilding, Gregory E, Cheng, Richard P, Glinsky, Vladislav V, Rittenhouse-Olson, Kate
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713588/
https://ncbi.nlm.nih.gov/pubmed/19649208
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