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Reduced acute brain injury in PGE(2) EP3 receptor–deficient mice after cerebral ischemia

Ischemic stroke is one of the leading causes of mortality and morbidity in humans. During brain ischemia and the subsequent reperfusion that occurs with stroke, the generation of the so-called “proinflammatory” prostaglandin E(2) (PGE(2)) increases significantly. Therefore, interest is growing regar...

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Bibliographic Details
Main Authors: Saleem, Sofiyan, Kim, Yun Tai, Maruyama, Takayuki, Narumiya, Shuh, Doré, Sylvain
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713583/
https://ncbi.nlm.nih.gov/pubmed/19203800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2009.01.015
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