The Lupane-type Triterpene 30-Oxo-calenduladiol Is a CCR5 Antagonist with Anti-HIV-1 and Anti-chemotactic Activities

The existence of drug-resistant human immunodeficiency virus (HIV) viruses in patients receiving antiretroviral treatment urgently requires the characterization and development of new antiretroviral drugs designed to inhibit resistant viruses and to complement the existing antiretroviral strategies...

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Main Authors: Barroso-González, Jonathan, El Jaber-Vazdekis, Nabil, García-Expósito, Laura, Machado, José-David, Zárate, Rafael, Ravelo, Ángel G., Estévez-Braun, Ana, Valenzuela-Fernández, Agustín
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713542/
https://ncbi.nlm.nih.gov/pubmed/19386595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.005835
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