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Stepwise Evolution of the Herpes Simplex Virus Origin Binding Protein and Origin of Replication
The herpes simplex virus replicon consists of cis-acting sequences, oriS and oriL, and the origin binding protein (OBP) encoded by the UL9 gene. Here we identify essential structural features in the initiator protein OBP and the replicator sequence oriS, and we relate the appearance of these motifs...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Biochemistry and Molecular Biology
2009
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713539/ https://ncbi.nlm.nih.gov/pubmed/19351883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807551200 |
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