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RARα2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myeloma
Specific genetic alterations in multiple myeloma (MM) may cause more aggressive diseases. Paired gene array analysis on 51 samples showed that retinoic acid (RA) receptor α (RARα) expression significantly increased at relapse compared with diagnosis. RARα encodes 2 major isoforms: RARα1 and RARα2. I...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713470/ https://ncbi.nlm.nih.gov/pubmed/19458357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-194126 |
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