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Toll-like receptor 2 (TLR2) deficiency leads to increased Th17 infiltrates in experimental brain abscesses

TLR2 plays a pivotal role in recognizing S. aureus, a common etiologic agent of CNS parenchymal infections, such as brain abscess. We previously reported that brain abscesses of TLR2 knockout (KO) mice exhibited elevated IL-17 levels, suggesting the presence of an alternative pathway available to re...

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Hlavní autoři: Nichols, Jessica R., Aldrich, Amy L., Mariani, Monica M., Vidlak, Debbie, Esen, Nilufer, Kielian, Tammy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713313/
https://ncbi.nlm.nih.gov/pubmed/19454709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802656
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