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The Effects of Repeated Opioid Administration on Locomotor Activity: I. Opposing Actions of μ and κ Receptors

Repeated administration of many addictive drugs leads to a progressive increase in their locomotor effects. This increase in locomotor activity often develops concomitantly with increases in their positive-reinforcing effects, which are believed to contribute to the etiology of substance use disorde...

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Detalhes bibliográficos
Main Authors: Smith, Mark A., Greene-Naples, Jennifer L., Lyle, Megan A., Iordanou, Jordan C., Felder, Jennifer N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713083/
https://ncbi.nlm.nih.gov/pubmed/19403853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.150011
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