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Arylphosphonium salts interact with DNA to modulate cytotoxicity
Arylphosphonium salts (APS) are compounds that have both lipophilic and cationic character, allowing them facile transport through plasma membranes or cell walls to accumulate in the cytoplasm or mitochondria of cells. APS molecules preferentially accumulate in tumor cells and are therefore under in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712833/ https://ncbi.nlm.nih.gov/pubmed/19429515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2009.01.002 |
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