Impaired vasodilator activity in DOCA-salt hypertension is associated with increased protein O-GlcNAcylation

Hyperglycemia, which increases O-linked β-N-acetylglucosamine (O-GlcNAc) proteins, leads to changes in vascular reactivity. Since vascular dysfunction is a key feature of arterial hypertension, we hypothesized that vessels from DOCA-salt rats exhibit increased O-GlcNAc-proteins, which is associated...

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Autors principals: Lima, Victor V., Giachini, Fernanda R.C., Choi, Hyehun, Carneiro, Fernando S., Carneiro, Zidonia N., Fortes, Zuleica B., Carvalho, Maria Helena C., Webb, R. Clinton, Tostes, Rita C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712827/
https://ncbi.nlm.nih.gov/pubmed/19139380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.116798
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