Loading...

Regulation of cancer invasiveness by the physical extracellular matrix environment

Long-term clinical outcomes are dependent on whether carcinoma cells leave the primary tumor site and invade through adjacent tissue. Recent evidence links tissue rigidity to alterations in cancer cell phenotype and tumor progression. We found that rigid extracellular matrix (ECM) substrates promote...

Full description

Saved in:
Bibliographic Details
Main Authors: Parekh, Aron, Weaver, Alissa M
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712813/
https://ncbi.nlm.nih.gov/pubmed/19458499
Tags: Add Tag
No Tags, Be the first to tag this record!