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Strong Correlation Between SHAPE Chemistry and the Generalized NMR Order Parameter (S(2)) in RNA

The functions of most RNA molecules are critically dependent on the distinct local dynamics that characterize secondary structure and tertiary interactions and on structural changes that occur upon binding by proteins and small molecule ligands. Measurements of RNA dynamics at nucleotide resolution...

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Detalhes bibliográficos
Main Authors: Gherghe, Costin M., Shajani, Zahra, Wilkinson, Kevin A., Varani, Gabriele, Weeks, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712629/
https://ncbi.nlm.nih.gov/pubmed/18710236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja804541s
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