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Maurocalcine and domain A of the II-III loop of the dihydropyridine receptor Ca(v)1.1 subunit share common binding sites on the skeletal ryanodine receptor

Maurocalcine is a scorpion venom toxin of 33 amino acid residues that bears a striking resemblance to the domain A. This domain belongs to the II-III loop of Ca(v)1.1 which is implicated in excitation-contraction coupling. Besides the structural homology, maurocalcine also modulates RyR1 channel act...

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Autors principals: Altafaj, Xavier, Cheng, Weijun, Estève, Eric, Urbani, Julie, Grunwald, Didier, Sabatier, Jean-Marc, Coronado, Roberto, De Waard, Michel, Ronjat, Michel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712624/
https://ncbi.nlm.nih.gov/pubmed/15591063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C400433200
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