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Vitreal Kinetics of Quinidine in Rabbits in the Presence of Topically Coadministered P-Glycoprotein Substrates/Modulators

The purpose of this study was to investigate whether topically administered P-glycoprotein (P-gp) substrates/modulators can alter vitreal kinetics of intravitreally administered quinidine. Male New Zealand rabbits were used under anesthesia. Vitreal kinetics of intravitreally administered quinidine...

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Detalhes bibliográficos
Main Authors: Majumdar, Soumyajit, Hippalgaonkar, Ketan, Srirangam, Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712438/
https://ncbi.nlm.nih.gov/pubmed/19406953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.026450
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