Matrix Metalloproteinase-9 Facilitates Glial Scar Formation in the Injured Spinal Cord

In the injured spinal cord, a glial scar forms and becomes a major obstacle to axonal regeneration. Formation of the glial scar involves migration of astrocytes toward the lesion. Matrix metalloproteinases (MMPs), including MMP-9 and MMP-2, govern cell migration through their ability to degrade cons...

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Autori principali: Hsu, Jung-Yu C., Bourguignon, Lilly Y. W., Adams, Christen M., Peyrollier, Karine, Zhang, Haoqian, Fandel, Thomas, Cun, Christine L., Werb, Zena, Noble-Haeusslein, Linda J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712293/
https://ncbi.nlm.nih.gov/pubmed/19074020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2287-08.2008
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