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A New Computational Approach for Mechanical Folding Kinetics of RNA Hairpins
Based on an ensemble of kinetically accessible conformations, we propose a new analytical model for RNA folding kinetics. The model gives populational kinetics, kinetic rates, transition states, and pathways from the rate matrix. Applications of the new kinetic model to mechanical folding of RNA hai...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712198/ https://ncbi.nlm.nih.gov/pubmed/19450474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.02.044 |
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