A New Computational Approach for Mechanical Folding Kinetics of RNA Hairpins

Based on an ensemble of kinetically accessible conformations, we propose a new analytical model for RNA folding kinetics. The model gives populational kinetics, kinetic rates, transition states, and pathways from the rate matrix. Applications of the new kinetic model to mechanical folding of RNA hai...

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Bibliographic Details
Main Authors: Cao, Song, Chen, Shi-Jie
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2009
Subjects:
Biophysical Theory and Modeling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712198/
https://ncbi.nlm.nih.gov/pubmed/19450474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.02.044
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