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A New Computational Approach for Mechanical Folding Kinetics of RNA Hairpins
Based on an ensemble of kinetically accessible conformations, we propose a new analytical model for RNA folding kinetics. The model gives populational kinetics, kinetic rates, transition states, and pathways from the rate matrix. Applications of the new kinetic model to mechanical folding of RNA hai...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712198/ https://ncbi.nlm.nih.gov/pubmed/19450474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.02.044 |
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