On the Function of Pentameric Phospholamban: Ion Channel or Storage Form?

Phospholamban (PLN) is an integral membrane protein that inhibits the sarcoplasmic reticulum Ca(2+)-ATPase, thereby regulating muscle contractility. We report a combined electrochemical and theoretical study demonstrating that the pentameric PLN does not possess channel activity for conducting chlor...

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Detalhes bibliográficos
Main Authors: Becucci, Lucia, Cembran, Alessandro, Karim, Christine B., Thomas, David D., Guidelli, Rolando, Gao, Jiali, Veglia, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Biophysical Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712152/
https://ncbi.nlm.nih.gov/pubmed/19450461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.013
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