Regulatory T cells fail to suppress CD4(+)T-bet(+) T cells in relapsing multiple sclerosis patients

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system and a defect in the regulatory T-cell subset seems to be involved in the pathogenesis of the disease. Foxp3 is a transcription factor that is selectively expressed in CD4(+) CD25(+) regulatory T cel...

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Bibliografiske detaljer
Main Authors: Frisullo, Giovanni, Nociti, Viviana, Iorio, Raffaele, Patanella, Agata K, Caggiula, Marcella, Marti, Alessandro, Sancricca, Cristina, Angelucci, Francesco, Mirabella, Massimiliano, Tonali, Pietro A, Batocchi, Anna P
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2009
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712110/
https://ncbi.nlm.nih.gov/pubmed/19016907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02963.x
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