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CD4(+) CD25(high) Foxp3(+) regulatory T cells downregulate human Vδ2(+) T-lymphocyte function triggered by anti-CD3 or phosphoantigen

Vδ2(+) T cells, the major circulating T-cell receptor-γδ-positive (TCR-γδ(+)) T-cell subset in healthy adults, are involved in immunity against many microbial pathogens including Mycobacterium tuberculosis. Vδ2(+) T cells recognize small phosphorylated metabolites (phosphoantigens), expand in respon...

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Autors principals: Mahan, C Scott, Thomas, Jeremy J, Boom, W Henry, Rojas, Roxana E
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712108/
https://ncbi.nlm.nih.gov/pubmed/19019089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02982.x
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