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Antimalarial activity of thiophenyl- and benzenesulfonyl-dihydroartemisinin

Each diastereomer of 10-thiophenyl- and 10-benzenesulfonyl-dihydroartemisinin was synthesized from artemisinin in three steps, and screened against chloroquine-resistance and chloroquine-sensitive Plasmodium falciparum. Three of the four tested compounds were found to be effective. Especially, 10β-b...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Seokjoon, Oh, Sangtae, Park, Gab-Man, Kim, Tong-Soo, Ryu, Jae-Sook, Choi, Han-Kyu
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Korean Society for Parasitology 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712013/
https://ncbi.nlm.nih.gov/pubmed/16192755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3347/kjp.2005.43.3.123
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