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Epistatic interactions modulate the evolution of mammalian mitochondrial respiratory complex components
BACKGROUND: The deleterious effect of a mutation can be reverted by a second-site interacting residue. This is an epistatic compensatory process explaining why mutations that are deleterious in some species are tolerated in phylogenetically related lineages, rendering evident that those mutations ar...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711975/ https://ncbi.nlm.nih.gov/pubmed/19523237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-266 |
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