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The non-apoptotic role of p53 in neuronal biology: enlightening the dark side of the moon

The transcription factor p53 protects neurons from transformation and DNA damage through the induction of cell-cycle arrest, DNA repair and apoptosis in a range of in vitro and in vivo conditions. Indeed, p53 has a crucial role in eliciting neuronal cell death during development and in adult organis...

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Autors principals: Tedeschi, Andrea, Di Giovanni, Simone
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711843/
https://ncbi.nlm.nih.gov/pubmed/19424293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.89
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