Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells

Reactive oxygen species (ROS) present in cigarette smoke (CS) are thought to contribute to the development of COPD. Although CS-ROS can hardly enter airway epithelial cells, and certainly not the circulation, systemic levels of ROS have been found to be elevated in COPD patients. We hypothesize that...

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Autores principales: van der Toorn, Marco, Rezayat, Delaram, Kauffman, Henk F., Bakker, Stephan J. L., Gans, Rijk O. B., Koëter, Gerard H., Choi, Augustine M. K., van Oosterhout, Antoon J. M., Slebos, Dirk-Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711811/
https://ncbi.nlm.nih.gov/pubmed/19411310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90461.2008
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