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Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells

Reactive oxygen species (ROS) present in cigarette smoke (CS) are thought to contribute to the development of COPD. Although CS-ROS can hardly enter airway epithelial cells, and certainly not the circulation, systemic levels of ROS have been found to be elevated in COPD patients. We hypothesize that...

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Detalhes bibliográficos
Main Authors: van der Toorn, Marco, Rezayat, Delaram, Kauffman, Henk F., Bakker, Stephan J. L., Gans, Rijk O. B., Koëter, Gerard H., Choi, Augustine M. K., van Oosterhout, Antoon J. M., Slebos, Dirk-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711811/
https://ncbi.nlm.nih.gov/pubmed/19411310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90461.2008
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