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Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cells

Migration of airway epithelial cells (AEC) is an integral component of airway mucosal repair after injury. The inflammatory cytokine IL-4, abundant in chronic inflammatory airways diseases such as asthma, stimulates overproduction of mucins and secretion of chemokines from AEC; these actions enhance...

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Hlavní autoři: White, Steven R., Martin, Linda D., Abe, Mark K., Marroquin, Bertha A., Stern, Randi, Fu, Xiaoying
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711809/
https://ncbi.nlm.nih.gov/pubmed/19447894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90453.2008
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