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Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema

Toll-like receptors (TLRs) of the innate immune system contribute to noninfectious inflammatory processes. We employed a murine model of hilar clamping (1 h) with reperfusion times between 15 min and 3 h in TLR4-sufficient (C3H/OuJ) and TLR4-deficient (C3H/HeJ) anesthetized mice with additional stud...

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Autori principali: Zanotti, Giorgio, Casiraghi, Monica, Abano, John B., Tatreau, Jason R., Sevala, Mayura, Berlin, Hilary, Smyth, Susan, Funkhouser, William K., Burridge, Keith, Randell, Scott H., Egan, Thomas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711808/
https://ncbi.nlm.nih.gov/pubmed/19376887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90406.2008
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