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Cellular Entry and Nuclear Targeting By a Highly Anionic Molecular Umbrella

A fluorescently-labeled, persulfated molecular umbrella (1) has been synthesized from cholic acid, lysine, spermine and Coumarin 343 and found capable of entering live HeLa cells. The distribution of 1 throughout the cytoplasm and the nucleus was diffuse and punctate, respectively. This finding, tog...

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Detalhes bibliográficos
Main Authors: Mehiri, Mohamed, Jing, Bingwen, Ringhoff, Danielle, Janout, Vaclav, Cassimeris, Lynne, Regen, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711778/
https://ncbi.nlm.nih.gov/pubmed/18681467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc8001826
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