Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2

Angiotensin converting enzyme (ACE) 2 activity and angiotensin-(1-7) [Ang-(1-7)] levels are increased in experimental cirrhosis; however, the pathways of hepatic Ang-(1-7) production have not been studied. This study investigated the role of ACE2, ACE, and neutral endopeptidase (NEP) in the hepatic...

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Detalhes bibliográficos
Main Authors: Herath, Chandana B., Lubel, John S., Jia, Zhiyuan, Velkoska, Elena, Casley, David, Brown, Lindsay, Tikellis, Chris, Burrell, Louise M., Angus, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711749/
https://ncbi.nlm.nih.gov/pubmed/19389807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00045.2009
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