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Periadventitial adipose tissue impairs coronary endothelial function via PKC-β-dependent phosphorylation of nitric oxide synthase

Endogenous periadventitial adipose-derived factors have been shown to contribute to coronary vascular regulation by impairing endothelial function through a direct inhibition of endothelial nitric oxide synthase (eNOS). However, our understanding of the underlying mechanisms remains uncertain. Accor...

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Détails bibliographiques
Auteurs principaux: Payne, Gregory A., Bohlen, H. Glenn, Dincer, Ü. Deniz, Borbouse, Léna, Tune, Johnathan D.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711722/
https://ncbi.nlm.nih.gov/pubmed/19482966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00116.2009
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