Rescue of skeletal muscle α-actin–null mice by cardiac (fetal) α-actin

Skeletal muscle α-actin (ACTA1) is the major actin in postnatal skeletal muscle. Mutations of ACTA1 cause mostly fatal congenital myopathies. Cardiac α-actin (ACTC) is the major striated actin in adult heart and fetal skeletal muscle. It is unknown why ACTC and ACTA1 expression switch during develop...

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Autors principals: Nowak, Kristen J., Ravenscroft, Gianina, Jackaman, Connie, Filipovska, Aleksandra, Davies, Stefan M., Lim, Esther M., Squire, Sarah E., Potter, Allyson C., Baker, Elizabeth, Clément, Sophie, Sewry, Caroline A., Fabian, Victoria, Crawford, Kelly, Lessard, James L., Griffiths, Lisa M., Papadimitriou, John M., Shen, Yun, Morahan, Grant, Bakker, Anthony J., Davies, Kay E., Laing, Nigel G.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2009
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711600/
https://ncbi.nlm.nih.gov/pubmed/19468071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200812132
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