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GNL3L stabilizes the TRF1 complex and promotes mitotic transition
Telomeric repeat binding factor 1 (TRF1) is a component of the multiprotein complex “shelterin,” which organizes the telomere into a high-order structure. TRF1 knockout embryos suffer from severe growth defects without apparent telomere dysfunction, suggesting an obligatory role for TRF1 in cell cyc...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711588/ https://ncbi.nlm.nih.gov/pubmed/19487455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200812121 |
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