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Inhibition of matrix metalloproteinases improves left ventricular function in mice lacking osteopontin after myocardial infarction
Osteopontin (OPN) plays an important role in left ventricular (LV) remodeling after myocardial infarction (MI) by promoting collagen synthesis and accumulation. This study tested the hypothesis that MMP inhibition modulates post-MI LV remodeling in mice lacking OPN. Wild-type (WT) and OPN knockout (...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711544/ https://ncbi.nlm.nih.gov/pubmed/18979185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-008-9939-6 |
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